Progressive Multifocal Leukoencephalopathy and Idiopathic CD4+Lymphocytopenia: A Case Report and Review of Reported Cases
نویسندگان
چکیده
منابع مشابه
Progressive multifocal leukoencephalopathy. A case report.
Progressive multifocal leukoencephalopathy (PML) is a progressive demyelinating disease caused by JC virus, occurring in immunocompromised patients. In the HAART era, approximately 5% of the AIDS patients have been reported to develop PML. The clinical presentation of PML is quite variable because lesions may occur anywhere in the CNS white mater; the most common fi ndings are motor weakness, v...
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The authors describe a case of primary progressive multifocal leukoencephalopathy (pPML). Unlike previous similar reports, our patient underwent up-to-date and extensive in vivo and post-mortem investigations that established beyond doubt the competence of his immune system and the absence of underlying predisposing disorders. The various implications of this case, both clinical and related to ...
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INTRODUCTION Progressive multifocal leukoencephalopathy is an opportunistic infection occurring in patients with severe cellular immunodeficiency. This case highlights the role of cellular immunodeficiency in the reactivation of John Cunningham virus in a case of an early stage plasmacytoma. CASE PRESENTATION A 76-year-old Caucasian woman presented with progressive left-sided hemiparesis, acc...
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Progressive multifocal leukoencephalopathy (PML) is a progressive lethal demyelinating disease of the brain, caused by JC virus. Reactivation of JC virus due to reduction of cellular immunity especially in setting of AIDS, is the commonest underlying cause. PML has classically been described in individuals with profound cellular immunosuppression such as patients with AIDS, haematological malig...
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BACKGROUND Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system which affects the white matter and is caused by reactivation of the JC polyomavirus. CASE REPORT We report the case of a 63-year-old man with chronic lymphocytic leukemia who was treated with fludarabine; rituximab and fludarabine; fludarabine, cyclophsphamide and rituximab; an...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2000
ISSN: 1058-4838,1537-6591
DOI: 10.1086/318120